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省时高效的光学系统优化吸入器的药物研究 - China Medical Device Manufacturer
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Fri, January 19th, 2018

2006年5/6月刊 » 技术新知
省时高效的光学系统优化吸入器的药物研究

定制的光电子设计使系统可以在 1 分钟内对药物器械组合产品进行检测。

新的光学系统可在60秒内对新器械和药物组合进行检测。该设备适用于吸入器和药物的检测,可缩短研发时间。该产品由Cambridge Consultants公司(英国剑桥; www.cambridgeconsultants.com)为VariDose公司(英国莱斯特郡,Loughborough)研制,采用定制光电子设计,对药物器械组合进行快速、高效的检测。该设备提供的信息还包括吸入器产生颗粒或液滴云雾的特征,设备亦可与其他测量设备、呼吸模拟器或者患者相连。吸入器的药物云雾通过导管时,被红、蓝和红外共面光束拦截检测。光线穿过扩散的药物云雾时,传感器可以对其结构进行监测。详细的分析结果会在标准的支持Windows操作系统的计算机上显示。检测结果可用于云雾基本特征的研究,例如颗粒大小分布的变异性和精细颗粒的比例。

全身性吸入剂的出现,以及全球对于哮喘和梗阻性肺病等呼吸系统疾病的关注,极大地激发了人们对于肺部给药系统的兴趣。据Cambridge Consultants公司介绍,目前的检测系统,如阶式撞击取样器(cascade impactor)和撞击器(impinger),灵活性差,操作费力,因此这种VariDose设备可以为药物研究带来更高的效率。

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