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高级聚碳酸酯材料促使血泵进入临床应用 - China Medical Device Manufacturer
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Sat, January 20th, 2018

2008 秋季刊 » 行业新闻
高级聚碳酸酯材料促使血泵进入临床应用

总部位于美国宾州的Renal Solutions公司(www.renalsolutionsinc.com)开发的血液透析泵,作为传统蠕动技术的替代品,对每个泵腔的柔性膜施加正、负压力以控制血流。该公司最初采用传统聚碳酸酯(PC)材料制造血泵,结果引起一种粘稠的情况。

公司负责运营及工程技术的高级副总裁John Maholtz先生表示:“透析过后,我们可以观察到纤维蛋白的产生和血凝块的形成,并粘附到泵壁上。”

RenalSolutions公司为此向沙伯基础创新塑料公司(美国麻州,Pittsfield;www.sabic-ip.com)咨询,尔后采用一种更加先进的材料代替聚碳酸酯。再辅之以对仪器设计稍作改良,问题终于迎刃而解。

RenalSolutions公司就血块粘附到聚碳酸酯材料上的问题与沙伯基础创新塑料公司进行商讨之后,决定尝试使用LexanHPM1944。该材料能满足血泵的物理和机械要求,并提供更佳的血液接触特性。Lexan HPM1944是一种生物相容性 聚碳酸酯,与传统聚碳酸酯相比,它能使血液中血小板的存留率提高50%,白细胞的活性降低50%,纤维蛋白原吸收量下降60%。

Maholtz先生说:“通过对设计和材料进行改良,我们似乎能够降低血泵中形成血栓和血凝块的可能性。事实上,初次使用6个小时后,Pulsar泵的壁上仍能保持清洁。”

与利用压力迫使血液通过透析仪的蠕动式泵不同,Pulsar泵采用压控两室设计推动血液缓慢移动。据该公司表示,血管梗塞时穿刺部位的压力很小,这对病人十分有利。该技术还可通过在图形用户界面上进行选择,转变为单针模式。RenalSolutions公司称,蠕动式泵的转换比较繁锁、复杂。Pulsar泵是RenalSolutions公司的Allient Sorbent血液透析系统的一项重要部件,该公司已于2007年11月被Fresenius Medical Care AG & Co.公司收购。

沙伯基础创新塑料公司,原GE塑料集团,是塑性树脂的全球供应商,服务多个行业。该公司致力于聚碳酸酯、ABS、ASA、PPE、PC/ABS、PBT和PEI树脂的制造和合成,此外还有Lexan、Cycolac和Ultem等品牌的特种材料。

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