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Fraunhofer开发出类骨硬质生物材料 - China Medical Device Manufacturer
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Fri, January 19th, 2018

2010年4月CMDM电子快讯 » 技术新知
Fraunhofer开发出类骨硬质生物材料

治疗韧带断裂的手术过程中,腿部的肌腱可以用来替代撕裂的韧带。肌腱通过钛金属干涉螺钉固定在骨骼上,而干涉螺钉必须在一定时间后取出。Fraunhofer研究院制造工程与应用材料研究所(IFAM;德国不来梅;www.ifam.fraunhofer.de)希望帮助十字韧带及其它骨科患者免除这一额外的手术。他们开发出了一种生物相容性螺钉,可随时间的推移实现生物降解。IFAM生物材料技术系主任Philipp Imgrund博士解释说:“我们对生物材料进行了改进,通过一种特殊的注塑工艺制成一种既坚硬又具有生物活性的可吸收螺钉。根据其组分,这些螺钉可以在24个月内实现生物降解。”采用聚乳酸制成的生物降解螺钉现已用于医疗领域,但其缺点在于它们降解之后会在骨骼中留下小洞。因此,IFAM研究人员对材料进行了改良,开发出了一种以聚乳酸和羟磷灰石(这种陶瓷材料是骨骼矿物的主要成分)为原料的可塑复合物。Imgrund说,“这种复合物的羟磷灰石含量更好,可以促进骨骼在植入物内部生长。”

IFAM的工程师开发出一种可以采用常规注塑方法进行精加工的生物材料颗粒,无需进行铣磨等后续加工处理。采用净成形工艺可将其加工成复杂的几何形状,从而获得质地坚硬的螺钉。

产品原型的特性与真正的骨骼非常接近,其耐压强度高于每平方毫米130 N(牛顿),而真正的骨骼耐压强度范围即在130 至180 N之间。此外,注塑工艺具有“节能”的副作用。一般而言,粉末注塑部件需要在高达1400 C的高温下铸压。Imgrund说,“我们的复合材料只需达到140 C即可。”工程师还打算在将来利用这种节能工艺开发其它生物植入物。

有关此项研究的详细信息,请访问Fraunhofer网站 www.fraunhofer.de/en/press/research-news/2010/03/bone-hard-bimaterial.jsp

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