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利用光线控制心脏起搏可促进新型起搏器的诞生 - China Medical Device Manufacturer
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Wed, January 17th, 2018

2010年9月CMDM电子快讯 » 技术新知
利用光线控制心脏起搏可促进新型起搏器的诞生

Lauren Gravitz在MIT主办的Technology Review杂志上报道称,研究人员首次利用光脉冲控制了一颗胚胎心脏的起搏速度。科学家们在一个出生两天的鹌鹑胚胎心脏上方1毫米处,放置了一束红外激光纤维。当他们改变激光脉冲的节奏时,心跳节奏也随之改变并与之相配。这项新技术在自然光子学杂志上发表,将会促进新型光学心脏起搏器的诞生。

美国俄亥俄州克利夫兰凯斯西保留地大学生物工程学博士后Michael Jenkins——这项研究的第一作者称“利用光的非侵入性心脏起搏与电刺激有各自的优缺点,它有可能被用于从基础研究到临床应用的所有领域。”

科学家们希望这种非侵入式的方法可以帮助揭示更多有关心脏发育和先天性心脏疾病的未知原因。“我们可以用它进行非侵入性研究,改变心率的环境变化是如何导致心脏缺陷的,或者,研究成长的关键阶段心率变化是如何改变基因表达的。”Jenkins说。

Jenkins还不能解释光线是如何导致心肌收缩的,他说这还需要数年时间。但其潜在的优点是毋庸置疑的。这种技术对手术中暴露的心脏起搏尤为有用。植入式心脏光起搏器——仍是一个遥远的前景——是一个方向,许多研究人员认为这值得追求。电动心脏起搏会导致心脏发育不良。虽然这对75岁病人来说不那么重要,但对于将心脏起搏器植入一个3岁孩子的儿科医生来说,是极大的担忧。

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