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软件将机器学习带给显微镜 - China Medical Device Manufacturer
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Wed, January 17th, 2018

2011年4月CMDM电子快讯 » 技术新知
软件将机器学习带给显微镜

位于德国海德堡的欧洲分子生物学实验室(EMBL)的科学家们发明出一种新的软件,这种软件将使研究人员坐在显微镜前几个小时,辛苦研究细胞的景象成为历 史。这一研究成果发表在科学期刊《自然方法》上(Micropilot微型实验: 以自动化荧光显微镜为基础的系统生物学成像),这种新软件可以快速掌握研究人员所寻找的物体,并自动进行复杂的显微试验。

软件名为Micropilot,它可以分析显微镜生成的低清晰形象,一旦它识别出科学家感兴趣的细胞,或者结构,它自动指示显微镜开始试验。 这一过程即可以像录制高清晰的时间推移影像一样简单,也可以如利用激光干涉荧光标记蛋白、并记录结果一样复杂。

开发人员表示,该软件可以更快地生成更多数据。 在四个无人操作的显微手术中,它在两个特定的细胞分裂过程中检测到232个细胞,并对它们进行复杂的影像试验。而一个经验丰富的显微镜工作者则需要至少工 作一个月才能在成千上万的样本中发现这些细胞。显微镜工作人员表示, 在如此高的吞吐量下,Micropilot能够轻易地快速生成足够的数据,并获得统计所需的可靠结果,使科学家们能够进一步分析在特定生物过程中发挥作用 的数百种不同蛋白。

Micropilot软件可以有公开的源代码。

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